One of the tips I used during my spring cleaning sweep was to refresh the mattress. Make it Do had a terrific how-to on cleaning a mattress. Basically, you dust that giant dust collector with baking soda and essential oil. I used half a box of soda and a liberal sprinkling of peppermint oil. I use the peppermint for other cleaning as well because it has antimicrobial properties.
After dusting the entire mattress with the soda/oil combination, I let it sit for a couple of hours. Then I vacuumed with the wand and brush attachment and was amazed at how heavy the canister became. There were a lot of dust mites and moisture that came out of our six-year-old bed. Then the room, heck -- the house, smelled so fresh, and nice, clean aromas of mint wafted up from the bed when we settled in for some intense sleeping. It was outstanding.
*I will be working on our bedroom this year, and yes, one of my goals is to make a new headboard so we're not sporting the inexpensive IKEA bed look anymore.